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The actos medicine gives the normal diet condition and exercise that improve the health. It mainly controls the patients who having the less insulin and with controls the non-insulin dependent diabetes. It mostly preferred by type 2 diabetes. Actos as the combination of drugs such as sulfonylurea, metformin etc. and this drugs control the glycemic cannot be reach the correct diet and plus exercises. For taking the actos having the dosage level. For daily once to use the actos means taking 15 or 30 mg tablet only. For taking the food only to use the actos and without food to actos that gives the side effect to the body. The main one to consult the doctor to take the actos dosage level. The actos works only the presence of insulin but the type 1 diabetic the patients should take the actos. The actos side effects for medication works in the human body that gives more side effects to the patients. The common side effect of actos that include: chest pain, decreased the urine outgoing, irregular breathing problem, swelling of face, fingers, feet and lower legs, tightness in chest, irregular range of heart beat, fatigue, dilated neck veins, liver problems etc. so first to consult the doctor to take the actos and don’t take the actos without consulting the doctors. For the federal health officers finding out the unexplained injuries using actos. For actos drug as pioglitazone HCL content that the affect the patients who are all having the type 2 diabetes patients. Most of the countries give the report about actos usage and demerits, symptoms.